Nitazoxanide

Generic for Alinia

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Available nationwide

What is Nitazoxanide?

Nitazoxanide is an antiprotozoal and antiviral medication used to treat infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia—two intestinal parasites commonly contracted through contaminated water or food. It's particularly important for treating Cryptosporidium in immunocompromised patients where the infection can be serious and prolonged. Nitazoxanide works by interfering with a key enzyme in anaerobic energy metabolism used by parasites. It's taken orally twice daily for 3 days, with the suspension form available for pediatric patients. Food improves absorption and tolerability.

Pyruvate ferredoxin oxidoreductase inhibition

Blocks PFOR, an enzyme essential to the anaerobic energy metabolism of Cryptosporidium and Giardia, disrupting the parasite's ability to generate energy and survive within the intestinal tract.

Dual parasite coverage

Effective against both Cryptosporidium parvum and Giardia lamblia with the same mechanism of action—providing reliable treatment for two of the most common causes of infectious diarrhea from contaminated water sources.

Short 3-day course

The full treatment requires only three days of twice-daily dosing, making it a convenient, well-tolerated regimen that's easy to complete fully—important for ensuring the infection is cleared completely.

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