Neffy

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Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Neffy?

Neffy is a prescription epinephrine nasal spray used for the emergency treatment of severe allergic reactions (anaphylaxis) including those triggered by insect stings, foods, medications, or unknown causes. It delivers epinephrine intranasally, providing a needle-free alternative to the EpiPen auto-injector. When anaphylaxis causes airways to swell shut and blood pressure to drop, Neffy rapidly reverses these life-threatening responses. It's designed for people who may hesitate to use an auto-injector and for those who find a nasal spray more accessible in an emergency. Like all epinephrine emergency treatments, it's a bridge to emergency medical care — not a substitute for calling 911.

Intranasal epinephrine delivery

Delivers a precise dose of epinephrine through the nasal mucosa directly into the bloodstream, bypassing the need for injection while achieving systemic drug levels fast enough to reverse anaphylaxis—the first FDA-approved needle-free epinephrine treatment for severe allergic reactions.

Rapid anaphylaxis reversal

Epinephrine causes immediate vasoconstriction, raises blood pressure, relaxes airway smooth muscle, and reduces vascular permeability—reversing the simultaneous cardiovascular and airway collapse that makes anaphylaxis life-threatening within minutes.

Needle-free accessibility

Designed to reduce the barrier to emergency epinephrine use—eliminating needle anxiety and the training required to use an auto-injector—while maintaining the speed and effectiveness needed to treat anaphylaxis before emergency responders arrive.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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