General MedicineGeneral Medicine
Megestrol

Megestrol

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is megestrol?

Megestrol is a synthetic progestin used primarily to stimulate appetite and promote weight gain in people experiencing significant weight loss and anorexia associated with cancer, HIV/AIDS, or other serious illnesses. At the doses used for appetite stimulation, it works through hormonal and metabolic pathways that increase hunger and improve caloric intake. It's also used in some cases to treat certain hormone-sensitive breast and endometrial cancers. Available in tablet and oral suspension form, it's taken once or multiple times daily depending on the indication.

Appetite stimulation

At higher doses, megestrol activates appetite-regulating pathways in the hypothalamus and may suppress pro-inflammatory cytokines like TNF-alpha and IL-6 that contribute to the anorexia and metabolic wasting seen in serious illness.

Weight and lean mass support

Promotes caloric intake and helps reverse unintentional weight loss in people with cancer- or HIV-related cachexia — improving nutritional status, energy levels, and overall quality of life.

Hormonal anti-tumor activity

As a progestin, megestrol can inhibit the growth of hormone receptor-positive breast and endometrial cancers by opposing estrogen's stimulating effects on tumor cell proliferation.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

5 out of 5 stars on Trustpilot

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

5 out of 5 stars on Trustpilot

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

5 out of 5 stars on Trustpilot

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

5 out of 5 stars on Trustpilot

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

5 out of 5 stars on Trustpilot

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

5 out of 5 stars on Trustpilot

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

5 out of 5 stars on Trustpilot

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