Lialda

Without insurance

With insurance

Compare prices at 50K+ pharmacies nationwide

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is Lialda?

Lialda is a prescription extended-release mesalamine tablet used to treat and maintain remission of mild to moderate ulcerative colitis. Lialda is an anti-inflammatory agent that works locally in the lining of the colon — where UC inflammation occurs — rather than systemically. Lialda's unique MMX multi-matrix delivery system releases the medication gradually throughout the entire colon, targeting the full extent of colonic inflammation with once-daily dosing. It's the first mesalamine formulation approved for once-daily dosing, which simplifies the treatment regimen compared to older 3 to 4 times daily formulations.

Local colonic anti-inflammatory action

Lialda inhibits prostaglandin and leukotriene synthesis in the colonic mucosa, reducing the inflammation that causes the bloody diarrhea, cramping, and urgency of ulcerative colitis — with activity concentrated in the colon rather than systemically.

MMX extended-release delivery

Lialda's multi-matrix technology creates a hydrophilic and lipophilic matrix that releases mesalamine progressively throughout the entire colon — ensuring drug reaches both the left and right colon where UC inflammation may be present.

Once-daily remission maintenance

Approved for once-daily dosing to induce and maintain remission, Lialda significantly reduces the daily pill burden compared to older mesalamine formulations — improving long-term adherence in a condition that typically requires ongoing therapy.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

Dive deeper: get the support you need

Your health rarely comes down to just one thing. If your clinician identifies related needs during your visit, we can help address them through additional services.

Medications

We will write your prescription and send it to your pharmacy

Lab tests

See cost up front and book your lab test instantly

Dermatology

Get a specialist consult or talk to a clinician about your condition

Travel needs

Going on a big trip? Get the vaccines and medications you need

Everyday care

No waitlist, rushed visits, or hidden fees—get care fast.

Frequently asked questions

What is General Medicine?

What can General Medicine help with?

General Medicine provides convenient care for all of your of health needs, including common and chronic conditions, specialist consultations, and preventative care. We make it easy to get the care you need—whether it's getting the right prescriptions, labs or imaging, or connecting you with the right specialists or in-person providers—ensuring your healthcare experience is seamless and stress-free.

How much does General Medicine cost?

Who is the care team at General Medicine?

How do you protect my health information?