Ibuprofen

Generic for Motrin

Without insurance

With insurance

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Most insurance accepted

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Available nationwide

What is Rx Strength Motrin (ibuprofen)?

Prescription-strength Motrin contains ibuprofen at higher doses than what's available over the counter, prescribed for moderate to severe pain, inflammation, and fever that don't respond adequately to standard doses. It belongs to the NSAID (non-steroidal anti-inflammatory drug) class and works by blocking the enzymes responsible for producing prostaglandins—the chemicals that trigger pain, swelling, and fever. It's used for conditions including arthritis, acute injuries, menstrual pain, and post-surgical pain. It's taken with food to minimize stomach irritation.

Prostaglandin synthesis inhibition

Blocks COX-1 and COX-2 enzymes that produce prostaglandins — the inflammatory mediators responsible for pain, swelling, and fever — reducing these symptoms at their biochemical source.

Higher-dose anti-inflammatory effect

Prescription doses provide greater anti-inflammatory activity than OTC ibuprofen, making it effective for conditions like arthritis and acute injuries where inflammation is the primary driver of pain and functional limitation.

Versatile pain and fever control

Effective across a broad range of pain types — musculoskeletal, inflammatory, menstrual, and post-procedural — giving clinicians a non-opioid option for moderate pain management.

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

What our customers have to say

4.7 stars from 550+ reviews

Everything is upfront

Everything is upfront and exactly what they state. No hidden costs or fees. Great experience!

Leslie

I felt heard and they followed through

I felt heard and they followed through until my prior authorization was approved after it was denied. They maintained communication with me until I received my medication.

Nichelle C

Got refills quickly and affordably

I needed medication refills, and they were able to fill them quickly and affordably.

Mya Harbison

Quick and easy from booking to Zoom

Everything was quick and easy from booking the blood work to our Zoom appointment. The doctor was pleasant and attentive.

Judy S

Listened and responded right away

The physician I was paired with listened to all of my concerns and responded right away. She was thorough, and I received my medication within hours.

Camille

Prescription confirmed within 45 minutes

I’d run out of a medication while I was in the process of changing doctors. I provided some information, and my prescription was done and confirmed within 45 minutes.

Mark

Thorough history check and a prompt prior authorization

They were very thorough in checking my medical history for any possible problems with the new medication, and very prompt in handling the prior authorization with the pharmacy and the insurance carrier.

Louis

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General Medicine provides convenient care for all of your of health needs, including common and chronic conditions, specialist consultations, and preventative care. We make it easy to get the care you need—whether it's getting the right prescriptions, labs or imaging, or connecting you with the right specialists or in-person providers—ensuring your healthcare experience is seamless and stress-free.

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