General MedicineGeneral Medicine
Estradiol

Estradiol

Without insurance

With insurance

Most insurance accepted

Board-certified clinicians

No hidden fees

Available nationwide

What is estradiol?

An oral estrogen medication, estradiol—the primary form of estrogen produced by the ovaries—is used to treat menopausal symptoms including hot flashes, night sweats, vaginal dryness, and mood changes. It's also used in hormone therapy for transgender women and in cases of premature ovarian insufficiency. Taken as a daily tablet, it restores estrogen levels that decline during and after menopause. For women with a uterus, a progestin is typically prescribed alongside it to protect the uterine lining from overstimulation.

Estrogen receptor activation

Binds to estrogen receptors throughout the body—in the brain, bones, cardiovascular system, and genitourinary tract—restoring the hormonal signaling that declines with menopause and drives its wide range of symptoms.

Hot flash and vasomotor relief

Directly addresses the hypothalamic thermoregulatory instability caused by estrogen deficiency, reducing the frequency and severity of hot flashes and night sweats that disrupt daily life and sleep.

Genitourinary and bone health

Restores vaginal tissue health, reduces urinary symptoms associated with genitourinary syndrome of menopause, and helps maintain bone density—protecting against the accelerated bone loss that follows estrogen decline after menopause.

Virtual visit with clinician

Ongoing support, always available.

Your care doesn’t end after your visit. Message your care team anytime to discuss side effects, ask questions about your medication, or request a refill.

We stay proactive so your care stays steady — adjusting your plan as needed and keeping you informed every step of the way.

Thousands of customers trust us

“I feel like I'm finally on the right path to improving my health with the right support now! It's so refreshing and reassuring.”

—Emerald, Texas

“My experience with General Medicine was amazing. The understanding and care that was taken to figure out what is exactly going on with me. I feel like a weight has been lifted off of me.”

—Kaylee, Louisiana

“I couldn't be happier with my experience with General Medicine! They are fast, responsive, kind and knowledgeable. It is much easier, more affordable and faster.”

—Nika, Tennessee

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